Human skin has evolved rapidly, leaving evolutionary signatures in the genome. The filaggrin (FLG) gene is widely studied for its skin-barrier function in humans. The extensive genetic variation in this gene, especially common loss-of-function mutations, has been established as primary risk factors for atopic dermatitis.To investigate the evolution of this gene, we analyzed 2,504 human genomes and genotyped the copy number variation of filaggrin repeats within FLG in 126 individuals......
The NCGIA was founded in 1988 as a National Science Foundation center for research in geographic information and its related technologies. The Center is based at three sites in the United States: here at Buffalo (NCGIA-Buffalo), at the University of California at Santa Barbara (NCGIA-UCSB), and at the University of Maine (NCGIA-Maine).More about NCGIA-Buffalo.
You are cordially invited to join the celebration of the Earth Day 2019, sponsored by the Department of Geography, NCGIA-UB, and the Geography Graduate Student Associations (GGSA). Earth Day is a world-wide annual event to demonstrate support for environmental protection.